Endocrine Abstracts

The trainee reps (Drs C Steele and R Besser) will provide an update on their activities on behalf of the trainees in the past year including:i) Update of the trainees’ section of the BSPED website.ii) Results of a recent survey of GRID trainees aimed to track training and for future workforce planning.iii) Ongoing activities (such as trainees’ section of the BSPED newsletter) and number of e-mail co...

Aims: To identify any improvements in BMD on NICE recommended treatments in patients with osteoporosis. Also to identify how many patients were taking calcium and vitamin D.Methods: Retrospective audit of 31 patients who had a DEXA scan between June 2011 and October 2012 at Birmingham City Hospital. Patient information was gathered from electronic data base (Clinical Data Archive). Inclusion criteria was at least two DEXA scan T-scores results, ...

Background and objectives: Obesity is associated with a relatively high prevalence of anaemia and iron deficiency compared to normal weight individuals; the cause is unknown. We aimed to determine the prevalence of iron deficiency and anaemia in a severely obese cohort of bariatric surgery candidates, and to explore underlying associations with markers of nutrition and inflammation.Methods: In a retrospective review of 703 consecutive patients presenting...

Background: Insulin pump therapy has been linked to improved HbA1c levels, reduced frequency of severe hypoglycaemic episodes and reduced rates of Diabetic Ketoacidosis compared to treatment with multiple daily injections. Insulin pump therapy was started in 2008 in our unit.Aims: To compare the metabolic effect of insulin pump therapy vs multiple daily injections via pen devices in children with type 1 diabetes in our unit.Method:...

We present a patient who was incidentally diagnosed with neonatal diabetes at 4 months of age. Due to his small size his treatment has posed a number of challenges for our team.Case Report: A 4 month old boy presented to the Emergency Department with a petechial rash on his legs. Investigations revealed elevated blood glucose of 26.7 mmol/l but a normal pH of 7.39. He had glycosuria but no ketonuria. There was no history of weight loss or osmotic symptom...

Familial hypocalciuric hypercalcaemia (FHH) is a rare autosomal dominant condition due to a mutation in the calcium-sensing receptor gene (CaSR). The CaSR is located on chromosome 3 and mutations are commonly heterozygote mutations causing loss of function. Heterozygote mutations demonstrate benign disease with mild, asymptomatic hypercalcaemia. Homozygous mutations in the CaSR usually present with neonatal severe hyperparathyroidism (NSHPT) in the first few weeks of life and ...

Background: The National Paediatric Diabetes Audit has identified inequalities in diabetes care. Children and young people (CYP) with Type 1 Diabetes Mellitus (T1DM) from both ethnic minority backgrounds and deprived areas are more likely to have reduced access to diabetes technologies and a higher HbA1c. In our service there was an inconsistent approach to the initiation of Continuous Glucose Monitoring (CGM) and use of insulin pumps. The introduction of a st...

Background: In the UK, Growth Hormone (GH) is indicated for treatment of children with short stature secondary to growth hormone deficiency (GHD), Prader Willi syndrome (PWS), Turner syndrome (TS), SHOX gene mutation, chronic renal insufficiency and born small for gestational age (SGA).Objectives: The aim was to assess the compliance of our local practice with the NICE guidance for GH therapy in children in addition to local guidance that TFTs and IGF-I ...

Background: The transition from paediatric to adult care can be challenging for patients with Type 1 diabetes. Poor contiuity of care provided by the diabetes team may worsen an already difficult time for these patients. Good transition of care is vital to minimise the risk of worsening patient outcomes. In 2016, two patients failed to transition from paediatric to adult diabetes care and subsequently received no adult appointment. This breakdown of continuity of care was a re...

Introduction: Since the outbreak of the COVID-19 pandemic, several cases of pituitary apoplexy following a SARS-CoV-2 infection have been described in several countries. Here, we describe a case series of pituitary apoplexy occurring in the aftermath of a SARS-CoV-2 infection to alert physicians about possible neuro-endocrinological damage caused by the virus that can lead to visual sequelae and hypopituitarism.Methods: We retrospectively identified all ...